Predicting adverse drug event using machine learning based on electronic health records: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Adverse drug events (ADEs) pose a significant challenge in current clinical practice. Machine learning (ML) has been increasingly used to predict specific ADEs using electronic health record (EHR) data. This systematic review provides a comprehensive overview of the application of ML in predicting specific ADEs based on EHR data.

Methods

A systematic search of PubMed, Web of Science, Embase, and IEEE Xplore was conducted to identify relevant articles published from the inception to 20 May 2024. Studies that developed ML models for predicting specific ADEs or ADEs associated with particular drugs were included using EHR data.

Results

A total of 59 studies met the inclusion criteria, covering 15 drugs and 15 ADEs. In total, 38 machine learning algorithms we

SUBMITTER: Hu Q 

PROVIDER: S-EPMC11600142 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature