Time-varying differences in stroke recurrence risk between types of atrial fibrillation based on screening methods and timing of detection.

ABSTRACT:

Introduction

Atrial fibrillation (AF) burden progresses with time. Among ischemic stroke (IS) patients, AF can be detected at different burden progression stages based on the timing and screening method. We hypothesized that AF detected after IS on 12-lead ECGs (ECG-AF) and via 14-day-Holter prolonged cardiac monitoring (AFDAS) are linked to lower IS recurrence risk than AF known before stroke occurrence (KAF) because of being at an earlier progression stage than KAF. Additionally, we posited that IS recurrence risk differences between AF types vary over time due to their differential progression stages.

Patients and methods

Retrospective observational cohort study including IS/TIA patients with KAF, ECG-AF, and AFDAS [2018-2021]. Adjusted hazard ratios (aHR) were estimated

SUBMITTER: Alvarado-Bolanos A 

PROVIDER: S-EPMC11600412 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature