Candida albicans cells exhibit media specific proteomic profiles during induction of filamentation.

ABSTRACT: Candida albicans is an opportunist pathogen responsible for a broad spectrum of infections, from superficial mycosis to the systemic disease candidiasis. C. albicans has various morphological forms, including unicellular budding yeasts, filamentous pseudohyphae and true hyphae, and the ability to switch from yeast to hyphal forms is a key survival mechanism underlying the adaptation of the pathogen to the microenvironments encountered within the host. Filamentation is regulated by multiple signalling pathways and its induction in different growth media in vitro has often led to conflicting results. In this study, we performed quantitative proteomic analyses to compare the response of C. albicans yeast cells grown in YNB minimal medium to those of cells grown in four media widely used in th

SUBMITTER: Veronique L 

PROVIDER: S-EPMC11600622 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature