Epidemiology of healthcare-associated bloodstream infection in South African neonatal units.

ABSTRACT:

Background

Reports of healthcare-associated bloodstream infection (HA-BSI) epidemiology in African neonatal units are limited.

Methods

We conducted a cross-sectional study (2017-2018) in nine neonatal units in the Western Cape Province, South Africa, including central, regional and district hospitals (416 beds) using laboratory and clinical records. Patient demographics, HA-BSI rates, pathogen spectrum, and hospital outcomes and empiric antibiotic coverage rates were determined.

Results

Over two years, 23,748 neonates were admitted with unit occupancy rates ranging from 79 to 93%. 485 HA-BSI episodes occurred, with median onset at 11 (IQR 7-24) days of life. Most HA-BSI episodes (348; 72%) affected very low birth weight neonates (< 1500 g). The overall HA-BSI rate was

SUBMITTER: Dramowski A 

PROVIDER: S-EPMC11600642 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature