Tissue source may affect the esophageal flora in patients with esophageal squamous cell carcinoma.

ABSTRACT: The aim of the present study was to provide a theoretical basis for the selection of standard sampling methods in the study of the esophageal microbiota in patients with esophageal squamous cell carcinoma (ESCC) by comparing the differences in bacterial communities between surgical and endoscopic esophageal mucosal tissues. A total of 72 patients with ESCC who were diagnosed at Taihe Hospital (Shiyan, China) between July 2018 and July 2019 were selected to participate in the present study. The sequence V₄ hypervariable region was amplified, and Illumina HiSeq sequencing was performed to analyze the differences between the two groups. The Shannon and Chao1 indices of the postoperative esophageal cancer tissue group samples (Group A) were higher than those of the esophageal mucosa

SUBMITTER: Liu XB 

PROVIDER: S-EPMC11600705 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature