A randomized trial of MONOFIX^® vs. V-loc™ for resection bed suture during robotic partial nephrectomy.

ABSTRACT:

Background

To evaluate the clinical efficacy and safety of Monofix^®-PDO compared to V-Loc™ for tumor bed suturing during robotic-assisted laparoscopic partial nephrectomy (RAPN).

Methods

A randomized, controlled, multicenter, single-blinded trial was conducted across four tertiary institutions. Patients with T1-2 stage renal masses scheduled for RAPN were enrolled. The exclusion criteria included patients not deemed in need of bed suturing, those with a history of prior chemotherapy or immunotherapy, and those with severe systemic diseases or high bleeding tendencies. A total of 174 patients participated and were subjected to permuted block randomization (T1a vs. others), resulting in 88 patients in the V-Loc™ group and 86 in the Monofix^®-PDO group. The

SUBMITTER: Han JH 

PROVIDER: S-EPMC11600744 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature