Development and validation of a rheumatoid arthritis case definition: a machine learning approach using data from primary care electronic medical records.

ABSTRACT:

Background

Rheumatoid Arthritis (RA) is a chronic inflammatory disease that is primarily diagnosed and managed by rheumatologists; however, it is often primary care providers who first encounter RA-related symptoms. This study developed and validated a case definition for RA using national surveillance data in primary care settings.

Methods

This cross-sectional validation study used structured electronic medical record (EMR) data from the Canadian Primary Care Sentinel Surveillance Network (CPCSSN). Based on the reference set generated by EMR reviews by five experts, three machine learning steps: 'bag-of-words' approach to feature generation, feature reduction using a feature importance measure coupled with recursive feature elimination and clustering, and classification usi

SUBMITTER: Pham ANQ 

PROVIDER: S-EPMC11600853 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature