Molecular characterization of human respiratory syncytial virus strains circulating among hospitalized children in Jordan.

ABSTRACT:

Background

Human Respiratory Syncytial Virus (HRSV) is a primary cause of severe pediatric respiratory infections, particularly in infants and young children, often resulting in hospitalization. The virus possesses a high degree of mutagenic potential, contributing to significant antigenic diversity, which complicates immune responses and poses challenges for vaccine development and disease management. This study was conducted in Jordan from 2022 to 2023 to epidemiologically determine the prevalence and molecular characteristics of RSV.

Methods

A total of 288 nasopharyngeal (NP) swabs were collected from hospitalized children at Prince Hamza Hospital, Amman, Jordan. All samples were screened for common viral and bacterial respiratory pathogens using PCR. A partial segment of

SUBMITTER: Khasawneh AI 

PROVIDER: S-EPMC11600855 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature