A matched analysis of the use of high flow nasal cannula for pediatric severe acute asthma.

ABSTRACT:

Rationale

The high-flow nasal cannula (HFNC) device is commonly used to treat pediatric severe acute asthma. However, there is little evidence regarding its effectiveness in real-world practice.

Objectives

We sought to compare the physiologic effects and clinical outcomes for children treated for severe acute asthma with HFNC versus matched controls.

Methods

This was a single-center retrospective matched cohort study at a quaternary care children's hospital. Children ages 2-18 hospitalized for severe acute asthma from 2015 to 2022 were included. Encounters receiving treatment with HFNC within the first 24 h of hospitalization were included as cases. Controls were primarily treated with oxygen facemask. Logistic regression 1:1 propensity score matching was done using d

SUBMITTER: Rogerson C 

PROVIDER: S-EPMC11601001 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature