SARS-CoV-2 coinfection in children with severe airway obstruction due to pulmonary tuberculosis.

ABSTRACT:

Introduction

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic had a significant impact on tuberculosis (TB) control globally, with the number of new TB diagnoses decreasing. Coinfection with some viruses, especially measles, could aggravate TB in children. This is presumably a result of depressed cellular immunity. Reports on children with TB and SARS-CoV-2 coinfection are limited.

Methods

A retrospective analysis of children up to 13 years old admitted to Tygerberg Hospital, Cape Town, South Africa, from March 2020 to December 2022 with suspected TB-induced airway compression requiring bronchoscopy. Children were included if they presented with severe intrathoracic airway obstruction and/or radiographic evidence of complicated TB. The patients were

SUBMITTER: Goussard P 

PROVIDER: S-EPMC11601029 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature