Comparing IOP-Induced Scleral Deformations in the Myopic and Myopic Glaucoma Spectrums.

ABSTRACT:

Purpose

To compare changes in macular curvature following acute IOP elevation across a range of myopic conditions.

Methods

We studied 328 eyes from 184 subjects, comprising 32 emmetropic controls (between +2.75 and -2.75 diopters), 50 eyes with high myopia (<-5 diopters; HM), 108 highly myopic with glaucoma (HMG) and 105 pathologic myopia (PM) eyes, and 33 PM with staphyloma (PM+S) eyes. For each eye, we imaged the macula using optical coherence tomography (OCT) under the baseline condition and under acute IOP elevation (to ∼40 mm Hg) achieved through ophthalmodynamometry. We manually aligned the scans (baseline and IOP elevation) using three vascular landmarks in the macula tissue. We then automatically segmented the sclera and the choroid tissues using a deep learning algo

SUBMITTER: Chuangsuwanich T 

PROVIDER: S-EPMC11601134 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature