A whole-genome scan for evidence of recent positive and balancing selection in aye-ayes (<i>Daubentonia madagascariensis</i>) utilizing a well-fit evolutionary baseline model.

ABSTRACT: The aye-aye (Daubentonia madagascariensis) is one of the 25 most endangered primate species in the world, maintaining amongst the lowest genetic diversity of any primate measured to date. Characterizing patterns of genetic variation within aye-aye populations, and the relative influences of neutral and selective processes in shaping that variation, is thus important for future conservation efforts. In this study, we performed the first whole-genome scans for recent positive and balancing selection in the species, utilizing high-coverage population genomic data from newly sequenced individuals. We generated null thresholds for our genomic scans by creating an evolutionarily appropriate baseline model that incorporates the demographic history of this aye-aye population, and identified

SUBMITTER: Soni V 

PROVIDER: S-EPMC11601216 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature