Reduced Vestibular Function is Associated with Cortical Surface Shape Changes in the Frontal Cortex.

ABSTRACT: Aging-associated decline in peripheral vestibular function is linked to deficits in executive ability, self-motion perception, and motor planning and execution. While these behaviors are known to rely on the sensorimotor and frontal cortices, the precise pathways involving the frontal and sensorimotor cortices in these vestibular-associated behaviors are unknown. To fill this knowledge gap, this cross-sectional study investigates the relationship between age-related variation in vestibular function and surface shape alterations of the frontal and sensorimotor cortices, considering age, intracranial volume, and sex. Data from 117 participants aged 60+ from the Baltimore Longitudinal Study of Aging, who underwent end-organ-specific vestibular tests (cVEMP for the saccule, oVEMP for the utric

SUBMITTER: Padova D 

PROVIDER: S-EPMC11601719 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature