The reproducibility of protocols used to mediate a current-induced vasodilation in the human cutaneous microcirculation.

ABSTRACT:

Introduction

Current-induced vasodilation (CIV) can be used to assess the prostacyclin (PGI2) pathway. This study, for the first time, evaluated the reproducibility of several protocols used to mediate a CIV.

Methods

Three CIV protocols were evaluated in 10 healthy participants who completed four testing sessions. Two testing sessions were conducted on the calf, separated by a period of seven days allowing interday reproducibility to be assessed. Two testing sessions were also conducted seven days apart on the forearm. At each testing session, cutaneous microvascular assessments were conducted for one hour on the right limb of interest before assessments were immediately performed on the left limb, allowing for intersite, intraday reproducibility to be evaluated. Assessments

SUBMITTER: Guigui A 

PROVIDER: S-EPMC11602075 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature