Gut microbiota markers in early childhood are linked to farm living, pets in household and allergy.

ABSTRACT:

Background

Children growing up on farms or with pets have a lower risk of developing allergy, which may be linked to their gut microbiota development during infancy.

Methods

Children from the FARMFLORA birth cohort (N = 65), of whom 28 (43%) lived on a dairy farm and 40 (62%) had pets, provided fecal samples at intervals from 3 days to 18 months of age. Gut microbiota composition was characterized using quantitative microbial culture of various typical anaerobic and facultatively anaerobic bacteria, with colonization rate and population counts of bacterial groups determined at the genus or species level. Allergy was diagnosed at three and eight years of age by experienced pediatricians. Generalized estimating equations were used to identify associations between farm residenc

SUBMITTER: Ljung A 

PROVIDER: S-EPMC11602077 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature