Stimulus-induced rotary saturation imaging of visually evoked response: A pilot study.

ABSTRACT: Spin-lock (SL) pulses have been proposed to directly detect neuronal activity otherwise inaccessible through standard functional magnetic resonance imaging. However, the practical limits of this technique remain unexplored. Key challenges in SL-based detection include ultra-weak signal variations, sensitivity to magnetic field inhomogeneities, and potential contamination from blood oxygen level-dependent effects, all of which hinder the reliable isolation of neuronal signals. This pilot study evaluates the performance of the stimulus-induced rotary saturation (SIRS) technique to map visual stimulation response in the human cortex. A rotary echo spin-lock (RESL) preparation followed by a 2D echo planar imaging readout was used to investigate 12 healthy subjects at rest and during continuous

SUBMITTER: Capiglioni M 

PROVIDER: S-EPMC11602267 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature