Inflammatory Th17 cells are correlated with insulin resistance and erythrocyte parameters in overweight and obese children.

ABSTRACT:

Introduction

Obesity is thought to be accompanied by chronic, low-grade, inflammation. The adipocytes are present in the subcutaneous and visceral fat tissue and contribute to the bone marrow cell compartment. Therefore, it poses a question whether the factors influencing adipocyte functions also have an impact on the hematopoietic function of the bone marrow. The aim of our study was to evaluate the association between erythrocyte parameters, the proinflammatory Th17 lymphocytes, and IR markers in children with excessive body weight.

Methods

A total of 27 overweight/obese and 15 normal-weight children aged 8-18 years were enrolled in the study. The analysis included anthropometric measurements, evaluation of Th17 cell frequency, erythrocyte parameters, and carbohydrate meta

SUBMITTER: Artemniak-Wojtowicz D 

PROVIDER: S-EPMC11602275 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature