Working memory related functional connectivity in adult ADHD and its amenability to training: A randomized controlled trial.

ABSTRACT:

Background

Working memory (WM) deficits are among the most prominent cognitive impairments in attention deficit hyperactivity disorder (ADHD). While functional connectivity is a prevailing approach in brain imaging of ADHD, alterations in WM-related functional brain networks and their malleability by cognitive training are not well known. We examined whole-brain functional connectivity differences between adults with and without ADHD during n-back WM tasks and rest at pretest, as well as the effects of WM training on functional and structural brain connectivity in the ADHD group.

Methods

Forty-two adults with ADHD and 36 neurotypical controls performed visuospatial and verbal n-back tasks during functional magnetic resonance imaging (fMRI). In addition, seven-minute resting

SUBMITTER: Tolonen T 

PROVIDER: S-EPMC11602582 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature