The proteome and metabolome changes distinguish the effect of dietary energy levels on the development of ovary in chicken during sexual maturity.

ABSTRACT: To deeply understanding the impact of peripheral energy level on the development of ovaries during the sexual maturation of chicken, in this study, the ovaries and serum of sexually mature and immature chickens at the same age from different energy level groups were collected, and the proteome and metabolome were detected. The results of ovarian and serum metabolomics revealed that dietary energy levels affected the energy metabolism and fatty acid oxidation of ovary in chicken, including the up-regulated expression of dihydroacetone phosphate and α-linolenic acid in high energy level groups. The results of proteomics showed that peripheral energy levels affected the catecholamine biosynthesis and metabolism in ovary before sexual maturation. The integrating analysis revealed that increase

SUBMITTER: Yin L 

PROVIDER: S-EPMC11602595 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature