Unravelling the role of mitochondrial DNA in hybrid incompatibility within species of the Anopheles gambiae complex.

ABSTRACT: Isolation mechanisms between mosquito species of the Anopheles gambiae complex, which includes major malaria vectors, remain poorly understood. In some cases, pre-zygotic barriers have been shown to limit gene flow between species of the complex, leading to a low level of hybridisation in nature. Post-zygotic mechanisms manifest with F₁ hybrid males fully sterile and F₁ hybrid females with reduced fertility. Genetic approaches combined with DNA sequencing techniques have highlighted the involvement of genomic regions in hybrid incompatibility with a predominant role of the X chromosome. In addition, differences in the phenotype of F₁ hybrid males have been identified depending on the directionality of the parental cross used to generate them. All these stud

SUBMITTER: Kriezis A 

PROVIDER: S-EPMC11603187 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature