Comparison of different noninvasive scores for assessing hepatic fibrosis in a cohort of chronic hepatitis C patients.

ABSTRACT: The continuous search for simple, noninvasive methods for assessing liver fibrosis remains very important to help risk-stratify and follow-up patients with chronic hepatitis C virus (HCV). This study aimed to evaluate the diagnostic performance and accuracy of six serological noninvasive scores for the assessment of liver fibrosis in comparison to liver histopathology. This retrospective cohort study included data from 19501 patients with chronic HCV infection who had liver biopsies as an HCV treatment prerequisite within the Egyptian national HCV treatment program. Six noninvasive scores (FIB-4, APRI, King's score, Fibro-Q, fibrosis index, Fibro-α score) were evaluated and compared to liver histopathology data in assessing different stages of liver fibrosis. The diagnostic performance for

SUBMITTER: El-Kassas M 

PROVIDER: S-EPMC11603190 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature