Comprehensive characterization of anthraquinones in <i>Damnacanthus indicus</i> using mass spectrometry molecular networking and metabolomics-based herb discrimination.

ABSTRACT: Damnacanthus indicus is a widely used folk medicine in China, renowned for its various bioactivities. The key active components, anthraquinones, have not been comprehensively profiled due to their complex chemical nature. Establishing a high-throughput strategy to systematically characterize these anthraquinones is essential. Additionally, the cultivation of D. indicus across various provinces results in significant quality differences in the harvested herbs. Thus, developing an effective strategy to distinguish herbs from different regions and identify characteristic chemical markers for quality evaluation and control is crucial. In this study, a strategy based on ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS) was employed to systematically charact

SUBMITTER: Zeng L 

PROVIDER: S-EPMC11603343 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature