Drug molecules beyond chemical biology: fluorescence- and DFT-based investigations for fluoride ion sensing and the trace detection of chloroform.

ABSTRACT: Excessive unmonitored use of fluoride has remained a threatening issue for a long time now as its long-term use is linked to several health issues. Similarly, chloroform is a highly carcinogenic solvent that requires proper monitoring. The increasing demand for a convenient, selective and sensitive fluoride and chloroform sensor intrigued us to utilize etoricoxib (ECX) as a sensor as it is highly safe and easily available. The photophysical properties of ECX, which were previously unexplored, were now studied with increasing water fractions and a significant aggregation-induced emission enhancement (AIEE) was seen through fluorescence spectroscopy. ECX was also successfully used for the trace level detection of chloroform through a significant emission enhancement. Similarly, the ECX-based

SUBMITTER: Shahzad SA 

PROVIDER: S-EPMC11603578 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature