Metastatic recurrence in women diagnosed with non-metastatic breast cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

To assess proportions of metastatic recurrence in women initially diagnosed with non-metastatic breast cancer by stage at diagnosis, breast cancer subtype, calendar period and age.

Methods

A systematic search of MEDLINE and Web of Science databases (January 2010-12 May 2022) was conducted. Studies reporting the proportion of distant metastatic recurrence in women with non-metastatic breast cancer were identified and outcomes and characteristics were extracted. Risk of bias was assessed independently by two reviewers. Random-effects meta-analyses of proportions were used to calculate pooled estimates and 95% confidence intervals (CIs).

Results

193 studies covering over 280,000 patients were included in the main analysis. Pooled proportions of metastatic recu

SUBMITTER: Morgan E 

PROVIDER: S-EPMC11603627 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature