Neurocognitive functioning in adults with neurofibromatosis type 1- a nationwide population-based study.

ABSTRACT:

Background

Neurofibromatosis type 1 (NF1) is a genetic condition characterized by various somatic manifestations and cognitive impairments, but the latter are sparsely described in adults. This study aimed at characterizing potential impairments of neurocognitive functions using neuropsychological tests as well as a self-report questionnaire.

Methods

In a nationwide, population-based study including 103 adults with NF1 and 38 age- and gender-matched NF1-free comparisons, we used a comprehensive neurocognitive test battery to assess intelligence and visual short-term memory, immediate visuospatial recall, reaction time, sustained attention, motor speed, planning, planning time, working memory as well as multitasking and a questionnaire to assess executive functions. Descripti

SUBMITTER: Doser K 

PROVIDER: S-EPMC11603635 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature