Mediating role of inflammatory biomarkers on the association of physical activity, sedentary behaviour with chronic kidney disease: a cross-sectional study in NHANES 2007-2018.

ABSTRACT:

Objectives

This study aims to investigate the association of physical activity (PA) and sedentary behaviour (SB) with chronic kidney disease (CKD), and to illustrate whether inflammatory biomarkers play a mediating role.

Design

A cross-sectional study.

Setting

This study analysed cross-sectional data from the National Health and Nutrition Examination Survey 2007-2018.

Participants

A total of 27 808 participants aged 20-80 years old were enrolled in the final analysis.

Outcome measures

PA and SB were self-reported by participants using the Global Physical Activity Questionnaire. Inflammatory biomarkers including neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR) and systemic immune inflammation index (SII) were examined in subjects' periph

SUBMITTER: Peng P 

PROVIDER: S-EPMC11603691 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature