Early-life menstrual characteristics and gestational diabetes in a large US cohort.

ABSTRACT:

Background

Associations between early-life menstrual cycle characteristics (MCC) and gestational diabetes (GDM) remain unclear.

Objectives

To evaluate associations between early-life MCCs and GDM in first pregnancy, across pregnancies and its recurrence.

Methods

This analysis included participants from a US-based digital cohort enrolled between 11/2019 and 9/2023 who provided consent, completed relevant surveys, were without diabetes and aged ≥18 at first pregnancy (n = 30,473). Age at menarche [<11 (early), 11-15 (referent), ≥16 (late) years] and time from menarche to cycle regularity [<1 (referent), 1-2, 3-4, ≥5 years, not yet regular, regular after hormones] were self-recalled at enrolment. Additionally, the last three categories were considered prolonged time-to-r

SUBMITTER: Wang Z 

PROVIDER: S-EPMC11603761 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature