Impact of gastrointestinal symptoms and psychological distress on quality of life in systemic sclerosis: a cross-sectional study.

ABSTRACT:

Background

Systemic sclerosis (SSc) is a chronic autoimmune disease characterised by microvascular damage and fibrosis. Mortality in patients with SSc has significantly decreased. Consequently, patients with SSc have longer life expectancy, and health-related quality of life (HrQoL) has become more relevant in the comprehensive management of the disease.

Objective

To evaluate the impact between gastrointestinal (GI) symptom burden and psychological well-being on HrQoL in patients with SSc.

Design

Nested cross-sectional study conducted between January and July 2022.

Participants

A single-centre cohort of 166 patients with SSc, including 103 (55%) with limited cutaneous SSc, 43 (24%) with diffuse SSc and 37 (21%) with sine-sclerosis SSc.

Main measures

GI s

SUBMITTER: Alcala-Gonzalez LG 

PROVIDER: S-EPMC11603815 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature