Liver histology pattern of young patients with inactive chronic hepatitis b virus infection from a hospital in South West Nigeria.

ABSTRACT:

Background

Chronic hepatitis B (CHB) infection is the leading cause of chronic liver disease in sub-Saharan Africa. A significant proportion of patients with CHB are inactive carriers, for whom guidelines neither recommend biopsy nor treatment. In sub-Saharan Africa, patients under 30 years old with CHB sometimes develop liver cancer, raising the possibility that significant liver disease may occur early in life in these patients.

Methods

A hospital-based cross-sectional study was conducted on patients with inactive CHB. A convenient sampling method was used to recruit patients. All patients underwent a percutaneous liver biopsy to evaluate significant necroinflammation and fibrosis using the Meta-analysis of histological data in viral hepatitis (METAVIR) system, defined as

SUBMITTER: Oje MM 

PROVIDER: S-EPMC11603992 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature