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Which is the better polyp detection metric: adenomas per colonoscopy or adenoma detection rate? A simulation modeling study.


ABSTRACT: Background and study aims We compared the ability of adenoma detection rate (ADR) and adenoma per colonoscopy (APC) to assess endoscopist detection, using statistical principles and simulations. Patients and methods We simulated a population of endoscopists and patients to compare the ability of ADR versus APC for capturing true endoscopist ability (TEA). We compared these rates with and without adjustment for patient and exam factors using multivariable models, and adjustment for imprecision due to low volume using empirical Bayes (shrinkage). Power calculations were used to compare the ability of ADR and APC to distinguish higher from lower rates over two time periods for an endoscopist. Results APC and ADR had similar discriminatory ability for assessing TEA. This i

SUBMITTER: MacKenzie T 

PROVIDER: S-EPMC11604309 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature