Characterization of intracranial compliance in healthy subjects using a noninvasive method - results from a multicenter prospective observational study.

ABSTRACT:

Purpose

An FDA-approved non-invasive intracranial pressure (ICP) monitoring system enables the assessment of ICP waveforms by revealing and analyzing their morphological variations and parameters associated with intracranial compliance, such as the P2/P1 ratio and time-to-peak (TTP). The aim of this study is to characterize intracranial compliance in healthy volunteers across different age groups.

Methods

Healthy participants, both sexes, aged from 9 to 74 years old were monitored for 5 min in the supine position at 0º. Age was stratified into 4 groups: children (≤ 7 years); young adults (18 ≤ age ≤ 44 years); middle-aged adults (45 ≤ age ≤ 64 years); older adults (≥ 65 years). The data obtained was the non-invasive ICP waveform, P2/P1 ratio and TTP.

Results

From Dece

SUBMITTER: Ocamoto GN 

PROVIDER: S-EPMC11604689 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature