The risk factors of lymph node metastasis in early colorectal cancer: a predictive nomogram and risk assessment.

ABSTRACT:

Purpose

Endoscopic procedures and surgery are common treatments for early colorectal cancer (CRC). However, only approximately 10% of patients who undergo surgery have lymph node metastases (LNM) detected on postoperative pathology, which often leads to overtreatment. This study aims to comprehensively analyze the risk factors for LNM in early CRC patients, establishing a predictive model to aid in treatment decisions.

Methods

This study reviewed the clinicopathologic data of patients with early CRC who underwent surgery from January 2015 to June 2023. Univariate and multivariate logistic regression analyses were employed to identify LNM risk factors. The receiver operating characteristic (ROC) analysis and calibration curves were also constructed to verify the model's discr

SUBMITTER: Xu J 

PROVIDER: S-EPMC11604734 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature