In vivo cardiac diffusion tensor imaging on an MR system featuring ultrahigh performance gradients with 200 mT/m maximum gradient strength.

ABSTRACT:

Purpose

Our aim is to assess the potential of an MR system with ultrahigh performance gradients (200 mT/m maximum gradient strength) to address two interrelated challenges in cardiac DTI: low SNR and sensitivity to bulk motion.

Methods

Imaging was performed in 20 healthy volunteers, two patients, and one swine post-myocardial infarction. The impact of maximum gradient strength was assessed with spin echo cardiac DTI featuring second-order motion compensation and varying maximum system gradient strengths (40, 80, 200 mT/m). Motion compensation requirements at 200 mT/m were assessed with sequences featuring zeroth-, first-, and second-order motion compensation. SNR, mean diffusivity, fractional anisotropy, helix angle transmurality, and secondary eigenvector angle in the left

SUBMITTER: Kara D 

PROVIDER: S-EPMC11604833 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature