Fast 3D ³¹P B 1 + mapping with a weighted stack of spiral trajectory at 7 T.

ABSTRACT:

Purpose

Phosphorus MRS (³¹P MRS) enables noninvasive assessment of energy metabolism, yet its application is hindered by sensitivity limitations. To overcome this, often high magnetic fields are used, leading to challenges such as spatial B 1 + $$ {\mathrm{B}}_1^{+} $$ inhomogeneity and therefore the need for accurate flip-angle determination in accelerated acquisitions with short TRs. In response to these challenges, we propose a novel short TR and look-up table-based double-angle method for fast 3D ³¹P B 1 + $$ {\mathrm{B}}_1^{+} $$ mapping (fDAM).

Methods

Our method incorporates 3D weighted stack-of-spiral gradient-echo acquisitions and a frequency-selective pulse to enable efficient B 1 + $$ {\mathrm{B}}_1^{+} $$ mapping based on the pho

SUBMITTER: Widmaier MS 

PROVIDER: S-EPMC11604843 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature