Compressed sensing reconstruction for high-SNR, rapid dissolved ¹²⁹Xe gas exchange MRI.

ABSTRACT:

Purpose

Three-dimensional hyperpolarized ¹²⁹Xe gas exchange imaging suffers from low SNR and long breath-holds, which could be improved using compressed sensing (CS). The purpose of this work was to assess whether gas exchange ratio maps are quantitatively preserved in CS-accelerated dissolved-phase ¹²⁹Xe imaging and to investigate the feasibility of CS-dissolved ¹²⁹Xe imaging with reduced-cost natural abundance (NA) xenon.

Methods

¹²⁹Xe gas exchange imaging was performed at 1.5 T with a multi-echo spectroscopic imaging sequence. A CS reconstruction with an acceleration factor of 2 was compared retrospectively with conventional gridding reconstruction in a cohort of 16 healthy volunteers, 5 chronic obstructive pulmonary disease pat

SUBMITTER: Pilgrim-Morris JH 

PROVIDER: S-EPMC11604844 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature