Palatoglossus Muscle and T4 Category in the Eighth Edition of TNM Staging System for OPSCC.

ABSTRACT:

Objective

The present study challenges the appropriateness of considering invasion of the palatoglossus muscle (PGM) as a criterion for staging oropharyngeal squamous cell carcinoma (OPSCC) as T4.

Study design

Retrospective observational study.

Setting

Tertiary University Hospital.

Methods

This retrospective study included nonmetastatic OPSCC patients treated with curative intent at the University of Trieste, Italy from 2015 to 2021. Patients were categorized into 4 groups: (1) tumors classified as T1-T2 by both International Cancer Control (UICC) and American Joint Committee on Cancer (AJCC)-TNM; (2) T1-T2 tumors upgraded to T4 solely by UICC due to oropharyngeal PGM infiltration; (3) T1-T2 tumors upgraded to T4 by both UICC and AJCC due to oral PGM infiltrati

SUBMITTER: Tirelli G 

PROVIDER: S-EPMC11605017 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature