Dwell time shaping in inverse treatment planning for cervical brachytherapy.

ABSTRACT: Manual treatment planning for cervical brachytherapy is a challenging task; therefore, we investigated a method for inverse treatment planning using pseudo-structures to control the dwell distribution. Our hypothesis was that this method could produce treatment plans with a pear-shaped dose distribution and a high central dose, that comply with clinical constraints. Data from 16 previously treated patients were used to compare three treatment planning methods: i) manual, ii) straightforward inverse, and iii) inverse with pseudo-structures. The treatment plans were compared using dose-volume histogram parameters and by analysing the dwell times, and the distribution of total reference air-kerma (TRAK) in the different parts of the applicator. Methods were evaluated in one treatment planning

SUBMITTER: Dohlmar F 

PROVIDER: S-EPMC11605463 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature