Routine invasive strategy and frailty burden in non-ST-segment elevation acute myocardial infarction.

ABSTRACT:

Objective

To assess the prognostic impact of a routine invasive strategy according to the frailty burden in patients with non-ST-segment elevation myocardial infarction (NSTEMI) from the MOSCA-FRAIL clinical trial.

Methods

The MOSCA-FRAIL trial randomized 167 frail patients, defined by a Clinical Frailty Scale (CFS) ≥ 4, with NSTEMI to an invasive or conservative strategy. The primary endpoint was the number of days alive and out of hospital (DAOH) one year after discharge. For this subanalysis, we compared the impact of an invasive strategy on the outcomes between vulnerable (CFS = 4, n = 43) and frail (CFS > 4, n = 124) patients.

Results

Compared to vulnerable patients, frail patients presented lower values of DAOH (289.8 vs. 320.6, P = 0

SUBMITTER: Ariza-Sole A 

PROVIDER: S-EPMC11605503 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature