Micellar "Click" Nanoreactors: Spiking Pluronic-Based Micelles with Polymeric Ligands.

ABSTRACT: In recent years, the development of nanoreactors, such as micellar nanoreactors (MNRs) for catalytic transformations, has gained significant attention due to their potential in enhancing reaction rates, selectivity, efficiency, and, as importantly, the ability to conduct organic chemistry in aqueous solutions. Among these, the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction represents a pivotal transformation and is widely used in the synthesis of bioconjugates, pharmaceuticals, and advanced materials. This study aims toward advancing our understanding of the design and utilization of polymeric amphiphiles containing tris-triazole ligands as an integral element for CuAAC reactions within MNRs. Specifically, our investigation delves into three critical factors that influence

SUBMITTER: Vippala K 

PROVIDER: S-EPMC11605775 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature