Integration of GWAS and transcriptomic analyses reveal candidate genes for duck gonadal development during puberty onset.

ABSTRACT:

Background

Puberty onset signifies the beginning of sexual maturation and reproductive phase in poultry indeed, and plays an essential role in genetics and breeding. Studying gonadal development is one of the important approaches to exploring the genetic mechanism of puberty onset.

Result

In our study, the phenotype data of the testes and ovaries of the 120-day-old Nonghua duck showed a large coefficient of variation, indicating that their gonads were in different developmental states. The CNV-based GWAS results for 358 Nonghua ducks showed two deleted-type CNVRs were associated with testicular weight (TW) and testicular percentage (TP), namely CNVR492 (Chr2: 59473501-59478500 bp) and CNVR494 (Chr2: 59514001-59517000 bp). Additionally, two both-type CNVRs were associated wit

SUBMITTER: Xu M 

PROVIDER: S-EPMC11605953 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature