Safety of Kidney Transplantation from Donors with HIV.

ABSTRACT:

Background

Kidney transplantation from donors with human immunodeficiency virus (HIV) to recipients with HIV is an emerging practice. It has been performed since 2016 under the U.S. congressional HIV Organ Policy Equity Act and is currently approved for research only. The Department of Health and Human Services is considering expanding the procedure to clinical practice, but data are limited to small case series that did not include donors without HIV as controls.

Methods

In an observational study conducted at 26 U.S. centers, we compared transplantation of kidneys from deceased donors with HIV and donors without HIV to recipients with HIV. The primary outcome was a safety event (a composite of death from any cause, graft loss, serious adverse event, HIV breakthrough infecti

SUBMITTER: Durand CM 

PROVIDER: S-EPMC11606542 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature