Performance of MR learned pulse sequences for 3D bi-exponential, stretched-exponential, and mono-exponential T₂ and T_1ρ mapping of knee cartilage.

ABSTRACT:

Purpose

To compare the performance of a learned magnetization-prepared gradient echo (L-MPGRE) sequence against a commonly used sequence for 3D T₂ and T_1ρ mapping of the knee joint, the magnetization-prepared angle-modulated partitioned k-space spoiled gradient echo snapshots (MAPSS), on bi-exponential (BE), stretched-exponential (SE), and mono-exponential (ME) relaxation models.

Methods

We used a combined differentiable and non-differentiable optimization to learn pulse sequence structure and its parameters for 3D T₂ and T_1ρ mapping of the knee joint using ME, SE, and BE models. The learned pulse sequence framework was used to improve quantitative accuracy and SNR and to reduce filtering effects. We compare the measured multi-comp

SUBMITTER: Zibetti MVW 

PROVIDER: S-EPMC11606783 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature