Kaempferol Reduces Cardiopulmonary Load and Muscular Damage in Repeated 400-m Sprints: A Double-Blind, Randomized, Placebo-Controlled Trial.

ABSTRACT: Plants exposed to hypoxic conditions have been suggested to produce more biologically active phytochemicals than those exposed to normal oxygen levels. Previously, we investigated 314 highland crop species and showed that the flavonoid kaempferol extracted from a highland quinoa grain markedly increased mitochondrial metabolism and ATP production in a hypoxic environment in vitro. Thus, we hypothesized that kaempferol would be effective during exercise under harsh conditions, in which anaerobic metabolism occurs. This study adopted a double-blind, placebo-controlled, crossover design to investigate the effect of a single oral dose of kaempferol (10 mg) on the athletic performance-related indicators of 13 male university athletes (20.8 ± 0.7 years) who performed two consecutive 400-m runs w

SUBMITTER: Okita K 

PROVIDER: S-EPMC11606868 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature