The association between chemosensitivity and the 10-year risk of type 2 diabetes in male patients with obstructive sleep apnea.

ABSTRACT:

Purpose

Obstructive sleep apnea (OSA) is associated with a variety of diseases, including type 2 diabetes (T2D). Chemosensitivity is an important component of the pathophysiological mechanisms of OSA, and it is not only elevated in patients with OSA but also in those with T2D. This study aimed to investigate the association between chemosensitivity and the risk of developing T2D in patients with OSA.

Methods

A total of 135 male participants with OSA and without pre-existing T2D were enrolled in this study. Peripheral chemosensitivity was evaluated using the rebreathing test. Data on demographics, polysomnographic parameters, and clinical characteristics were collected. The QDiabetes-2018 risk calculator was employed to calculate the 10-year T2D risk. The association between

SUBMITTER: Wang L 

PROVIDER: S-EPMC11607132 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature