Research Letter: Relationship of Blood Biomarkers of Inflammation With Acute Concussion Symptoms and Recovery in the CARE Consortium.

ABSTRACT:

Objective

Determine the association of inflammatory biomarkers with clinical measures and recovery in participants with concussion.

Setting

Multicenter study in National Collegiate Athletic Association member institutions including military service academies.

Participants

Four hundred twenty-two participants with acute concussion.

Design

Clinical visits and blood draws were completed preinjury and at multiple visits postconcussion (0-12 hours, 12-36 hours, and 36-60 hours postinjury). Clinical measures included Sport Concussion Assessment Tool (SCAT) symptom severity, Balance Error Scoring System, Standardized Assessment of Concussion (SAC), Brief Symptom Inventory-18 (BSI-18) scores, time to initiation of graduated return-to-play (RTP) protocol, and time to RT

SUBMITTER: Meier TB 

PROVIDER: S-EPMC11607172 | biostudies-literature | 2025 Jan-Feb 01

REPOSITORIES: biostudies-literature