Comparative genomics and virulence potential of Campylobacter coli strains isolated from different sources over 25 years in Brazil.

ABSTRACT:

Background

Campylobacter spp. have been reported as a common cause of gastroenteritis in humans in many countries. However, in Brazil there is insufficient data to estimate the impact of Campylobacter in public health. In light of the importance of this foodborne pathogen, the aim of this study was to perform comparative analyses on 80 Brazilian Campylobacter coli genomes isolated from human feces, animals, the environment, and food. Methods include Average Nucleotide Identity (ANI), Gegenees, genomic plasticity, presence of pathogenicity, resistance, and metabolic islands. In addition, virulence analysis in Galleria mellonella were also performed for 18 selected C. coli strains.

Results

The ANI values confirmed that all strains belonged to the C. coli species. Phylogenetic

SUBMITTER: Gomes CN 

PROVIDER: S-EPMC11607955 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature