Comprehensive compilation of congener profiles to support health assessment of environmental exposures to polychlorinated biphenyl mixtures.

ABSTRACT: Exposure to polychlorinated biphenyls (PCBs) remains a potential human health risk due to their persistence in the environment, despite a global ban on their production. Understanding the composition of PCB mixtures is essential for the application of a mixtures-based approach to assessing health risks of PCB exposure. This work represents the most extensive effort to date to compile and make publicly available the PCB congener profiles for mixtures with toxicological data, providing a foundation for understanding toxicological potency of PCB mixtures in the environment. We searched for published congener profiles across 29 commercial and simulated environmental PCB mixtures, including various Aroclors, Phenoclors, Clophens, and Kanechlors, among others. A total of 117 references containin

SUBMITTER: Schulz B 

PROVIDER: S-EPMC11608150 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature