Predicting risk factors for postoperative intestinal stenosis in neonates with necrotizing enterocolitis: development and assessment of a predictive nomogram.

ABSTRACT:

Objective

The aim of this study was to develop and validate an intestinal stenosis prediction model for postoperative newborns with neonatal necrotizing enterocolitis (NEC).

Methods

Clinical information was collected on neonates who had undergone anastomosis or enterostomy because of NEC. The least absolute shrinkage and selection operator regression was applied to identify risk factors included in the model for postoperative intestinal stenosis. Multivariate logistic regression analysis was used to develop a predicting model regression based on the selected variables. Then internal validation was assessed using the bootstrapping validation. The accuracy and applicability of the model are assessed by C-index, calibration and decision curve.

Results

Predictors incorpor

SUBMITTER: Chen Y 

PROVIDER: S-EPMC11608343 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature