Aminotransferase-to-lymphocyte ratio as a valuable prognostic marker for patients with stage I-III colorectal cancer: a retrospective study.

ABSTRACT:

Background

There are no population-based studies on the prognostic value of the preoperative aminotransferase-to-lymphocyte ratio (AALR) in predicting recurrence and survival in patients with colorectal cancer (CRC) who have undergone curative resection.

Aim

This study explored the relationship between AALR and prognosis of CRC patients, specifically stage III CRC.

Methods

Restricted Cubic Splines were used to evaluate the relationship between AALR and outcomes. The survival curve was generated using the Kaplan-Meier method and the log-rank test. COX regression analysis was used to identify the independent prognostic factors of CRC patients. Logistic regression analysis was used to assess the independent risk factors affecting sarcopenia and postoperative complication

SUBMITTER: Xie H 

PROVIDER: S-EPMC11609077 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature