Organizing space through saccades and fixations between primate posterior parietal cortex and hippocampus.

ABSTRACT: The primate posterior parietal cortex (PPC) withholds a unified representation of the visual space supporting visual exploration, while the hippocampus (HPC) provides a memory-based cognitive place map of the environment. To probe the interactions between these two representations, i.e. between view and place, we compared neural activity in the two regions of macaques navigating a virtual maze. We show that a large proportion of PPC neurons displayed spatial selectivity, along with the HPC. We hypothesized that such modulation by self-position might stem from visual cues processing through saccades and fixations. Accordingly, we found saccade-modulated neurons and cells driven by direct fixations on maze paths or landmarks in both brain regions. These populations of "path" and "landmark ce

SUBMITTER: Vericel ME 

PROVIDER: S-EPMC11609276 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature